Seraph on the Suwanee is the compelling story of two people at once deeply in love and deeply at odds. The heroine, young Arvay Henson, is convinced she will never find true love and happiness, and defends herself from unwanted suitors by throwing hysterical fits and professing religious fervor. Arvay meets her match, however, in handsome Jim Meserve, a bright, enterprising young man who knows that Arvay is the woman for him, and refuses to allow her to convince him otherwise.